On the Meaning of Affinity Limits in B-Cell Epitope Prediction for Antipeptide Antibody-Mediated Immunity

Figure 3

On- and off-rates of antipeptide antibodies binding their epitopes, obtained by surface plasmon resonance (SPR). For reactions of antipeptide antibodies with peptides, data points are labeled either by affinity rank in Figure 2 for corresponding IEDB records on affinity data or, where such records were not found, alphabetically with uppercase letters in order of decreasing affinity [76]. For cross-reactions of antipeptide antibodies with protein [76], data points are labeled with lower-case letters (i and k) matching the uppercase letter labels (I and K) of data points for the corresponding reactions of the antibodies with peptide.