Research Article
Detecting Cancer Outlier Genes with Potential Rearrangement Using Gene Expression Data and Biological Networks
Table 1
Pathway enrichment analysis for rearranged gene,
values are in (), FDR < 0.005.
| | Prostate | Ovarian | Leukemia |
| | Drug metabolism (<0.0000) | Receptor-ligand complexes (<0.0000) | Integrin cell surface interaction (<0.0000) | | Retinol metabolism (<0.0000) | Cadherin signaling pathway (<0.0000) | Focal adhesion (<0.0000) | | Toll-like receptor signaling (<0.0000) | Regulation of B-cell development (0.0001) | ECM-receptor interaction (<0.0000) | | Estrogen responsive protein (0.0003) | Wnt signaling (0.001) | Wnt signaling pathway (<0.0000) | | Receptor-ligand complex (0.001) | Protein kinase (0.001) | Signaling by PDGF (<0.0000) | | Signaling by Rho GTPases (0.004) | Signaling by FGFR (0.002) | Formation of platelet plug (<0.0000) | | P53 signaling (0.005) | PPAR signaling (0.004) | Regulation of bone mineralization (<0.0000) | | FOXA transcription (0.005) | Calcium signaling pathway (0.004) | Pathways in cancer (0.0001) |
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