Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE

Figure 2

PDIA3P1 depletion and trophoblast proliferation. (a) Validation of cell proliferation viability in si-PDIA3P1-transfected HTR-8/SVneo cells. (b) CCK-8 assays determined the proliferation of JAR cells post PDIA3P1 siRNA transfection. EdU assays illustrated the proliferation of HTR-8/SVneo (c) and JAR cells (d) following siPDIA3P1 transfection. (e) Flow cytometry evaluated the impact of si-PDIA3P1 on the cell cycle in HTR-8/SVneo and JAR cells. On the right is the quantification of cell cycle (f). Data are reported as mean ± SD. ; .

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