Review Article
Concepts and Treatment Approaches in Nonalcoholic Fatty Liver Disease
Table 1
Noninvasive diagnostic methods for nonalcoholic fatty liver disease.
| Method | Pros | Cons |
| Combined clinical and plasma scoring systems | Low cost, widely available, and acceptable diagnostic accuracy | Need for greater validation, decreased accuracy for staging fibrosis | Plasma CK-18 | Can differentiate NAFLD or NASH and if fibrosis present | Not widely available, need for greater validation | Ultrasonography | Low cost, widely available, and safe | Liver fat not quantifiable and low sensitivity if <30% | Transient elastography | Safe, easy to use, and large probe for obese patients available | Expensive equipment, need for greater validation | Magnetic resonance elastography | Quantifies liver fat and can evaluate for fibrosis with good histology correlation | Expensive equipment, expensive testing, limited availability, and body size constraints |
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