HISORt criteria for IgG4 associated cholangitis [26].
Feature
Characteristics
Histology of bile duct
Lymphoplasmacytic sclerosing cholangitis on resection specimens (lymphoplasmacytic infiltrate with >10 IgG4-positive cells/high powered field within and around bile ducts with associated obliterative phlebitis and storiform fibrosis)
Imaging of bile duct
(i) One stricture or more strictures involving intrahepatic, proximal extrahepatic, or intrapancreatic bile ducts (ii) Fleeting/migrating biliary strictures
Serology
Increased levels of serum IgG4
Other organs involvement
pancreas, retroperitoneal fibrosis, renal lesion, and salivary/lacrimal gland
Response to steroid therapy
Normalization of liver enzymes or resolution of stricture (radiologically)
