Review Article

Hepatitis B Virus Infection and the Kidney: Renal Abnormalities in HBV Patients, Antiviral Drugs Handling, and Specific Follow-Up

Table 1

International definition and stratification of kidney disease by the K/DOQI and the KDIGO.

StageDescriptionGFR (mL/min/1.73 m2)

Patients at increased riskRisk factors for kidney disease (e.g., diabetes, high blood pressure, family history, older age, etc.)More than 90
1Kidney damage and normal GFRMore than 90
2Kidney damage and mild decrease in GFR60 to 89
3Moderate decrease in GFR30 to 59
4Severe decrease in GFR15 to 29
5Kidney failure (dialysis or kidney transplant needed)Less than 15

GFR: glomerular filtration rate; CrCl: creatinine clearance; signs of kidney damage may include proteinuria and hematuria.