Review Article

Hepatitis B Virus Infection and the Kidney: Renal Abnormalities in HBV Patients, Antiviral Drugs Handling, and Specific Follow-Up

Table 6

Drug dosing recommendations for telbivudine in CHB patients with CKD.

eGFR (mL/Min)Dosage recommended
Oral solutionTablets

≥90600 mg/day600 mg/day
<90–60600 mg/day600 mg/day
<60–30400 mg/day600 mg every 48 hours
<30–15200 mg/day600 mg every 72 hours
<15120 mg/day600 mg every 96 hours
HD*120 mg/day600 mg every 96 hours
CAPDNDND

*On hemodialysis days, telbivudine should be administered after the session.
eGFR: estimated glomerular filtration rate; ND: no data.
Source: http://www.sitegpr.com/.