Research Article

Outbreak of Serratia marcescens in the Neonatal Intensive Care Unit of a Tertiary Care Hospital in Mexico

Table 1

Clinical characteristics of the S. marcescens outbreak cases in the neonatal intensive care unit of the Women’s Hospital in Sinaloa, Mexico.

Nos.GenderAdmission age (hours)Admitting diagnosisPregnancy status (w)Admission weight (g)Hospital days before S. marcescens isolationProcedures before the symptomsPrevious antibiotics therapySymptomsAntibiotics therapyFinal diagnosisHospital days until dischargeOutcome

1M4TTNTerm (39)28702CPAP, nasal tips, peripheral catheter, parenteral solutionsNotRespiratory distress, vomiting, abdominal distension, jaundice, hepatosplenomegaly, fever, pallor, skin color changes, thrombocytopenia, and ventricular hemorrhageYesSepsis respiratory5Death

2F24TTN/SDRTerm (40)29001CPAP, intubation, mechanical ventilation, umbilical catheterNotRespiratory distress, jaundice, fever, thrombocytopeniaYesSepsis respiratory18Health improvement

3M11TTN/ARDS/respiratory depressionPreterm (36)32501NIPPV, intubation, umbilical catheter, mechanical ventilation, parenteral solutionsNotRespiratory distress, abdominal distension, jaundice, hepatosplenomegaly, fever, pallor, skin color changes, hypoactivityYesSepsis respiratory21Health improvement

4F24APGAR low score/neonatal asphyxiaTerm (39)32001NIPPV, peripheral catheter, parenteral solutionsNotRespiratory distress, jaundice, fever, pallor, thrombocytopeniaYesSepsis respiratory20Health improvement

5M6Sepsis risk by poor prenatal controlTerm (39)31502Peripheral catheter, parenteral solutionsYesRespiratory distress, vomiting, abdominal distension, fever, thrombocytopeniaYesSepsis respiratory21Health improvement

6M24TTRN/ARDSPreterm (32)16001CPAP, intubation, umbilical catheter, and parenteral solutionsNotRespiratory distress, jaundice, fever, pallor, thrombocytopenia, and lung hemorrhageYesSepsis respiratory30Health improvement
7M27TTRN/ARDSTerm (39)29303CPAP, nasal tips, umbilical catheter, and parenteral solutionsNotRespiratory distress, abdominal distension, skin color change, hypoactivity, thrombocytopenia, digestive hemorrhageYesSepsis respiratory14Health improvement

8M24TTN/ARDS/sepsis risk by maternal cervicovaginitisPreterm (36)24704NIPPV, CPAP, intubation, umbilical catheter, parenteral solution, orogastric tubeYesRespiratory distress, jaundice, fever, pallor, skin color change, hypoactivity, digestive-ventricular hemorrhagesYesSepsis respiratory40Transferred to another hospital

9M18TTN/ARDS/neonatal asphyxia/perinatal asphyxia/MASTerm (39)34008NIPPV, intubation, umbilical catheter, and parenteral solutionsNotJaundice, fever, skin color change, thrombocytopeniaYesSepsis respiratory27Health improvement

10F6TTN/ARDSPreterm (35)27001NIPPV, CPAP, umbilical catheter, and parenteral solutionsNotRespiratory distress, abdominal distension, jaundice, hepatosplenomegaly, fever, skin color change, hypoactivity, thrombocytopenia, digestive hemorrhageYesSepsis respiratory15Health improvement

11M36TTN/ARDSTerm (37)26205CPAP, nasal tips, umbilical catheter, peripheral catheter, and parenteral solutionsNotVomit, jaundice, hepatosplenomegaly, hypoactivity, thrombocytopeniaYesSepsis respiratory16Health improvement
12M48TTN/ARDSTerm (38)33203CPAP, nasal tips, umbilical catheter, and parenteral solutionsNotJaundice, fever, pallor, skin color change, thrombocytopeniaYesSepsis respiratory15Health improvement

13M20TTN/ARDSPreterm (36)35001CPAP, umbilical catheter, and parenteral solutionsYesRespiratory distress, abdominal distension, jaundice, hepatosplenomegaly, fever, pallor, skin color change, hypoactivity, hemorrhagesYesSepsis respiratory17Health improvement

14M11TTN/ARDS/neonatal asphyxiaPreterm (36)29101NIPPV, CPAP, intubation, mechanical ventilation, umbilical catheter, and parenteral solutionsNotSkin color changes, hypoactivity, and thrombocytopeniaYesSepsis respiratory13Health improvement

15F31Neonatal jaundice/early-onset neonatal sepsisPreterm (35)29301No proceduresNotNo symptomsYesColonization11Health improvement

Nos.: numbers, TTN: transient tachypnea of the newborn, ARDS: acute respiratory distress syndrome, MAS: meconium aspiration syndrome, w: weeks, NIPPV: intermittent positive pressure ventilation, and CPAP: continuous positive airway pressure. : the patient was transferred for requiring procedures that the hospital did not have, and the patient left the hospital infection-free.