Associated Biochemical and Hematological Markers in COVID-19 Severity Prediction
Table 3
Predictive efficacy of the severe COVID-19 risk model and early predictors.
Test variables
AUC
SE
95% CI
Cut-off point
Sensitivity (%)
Specificity (%)
value
D-dimer (ng/ml)
0.874
0.021
0.824–0.924
0.91
82.2
81.2
0.001
Age (years)
0.656
0.031
0.577–0.736
54.5
71.1
63.4
0.001
CRP (mg/dl)
0.857
0.047
0.803–0.910
82.4
82
75.2
0.001
Neutrophil (%)
0.774
0.043
0.706–0.842
78.5
73.3
72.3
0.001
LDH (U/L)
0.762
0.023
0.691–0.833
600
71.1
66.4
0.001
ALT (U/L)
0.648
0.012
0.566–0.730
35.5
60.0
54.0
0.001
Ferritin (ng/ml)
0.750
0.036
0.591–0.745
43.5
80.0
59.4
0.001
ALT: alanine transferase; AST: aspartate transferase; ALP: alkaline phosphatase; LDH: lactate dehydrogenase; AUC: area under curve; CI: confidence interval. value indicates the level of significance.
