Review Article
Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics
Table 2
ATM-deficiency in cancer.
| Malignancy | ATM-deficient cell lines/number tested |
| T-cell prolymphocytic leukemia [73] | 17/32 | Mantle cell lymphoma [53] | 12/28 | Rhabdomyosarcoma [74] | 7/17 | Chronic lymphoblastic leukemia [54, 73] | 16/50, 38/111 | BRCA1-negative breast cancer [75] | 12/36 | BRCA2 negative breast cancer [75] | 12/40 | Acute lymphoblastic leukemia [54] | 4/15 | Non-BRCA1/BRCA2 negative breast cancers [75] | 118/1106 | Other lymphomas [53] | 10/97 |
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