Review Article
Rett Syndrome: Coming to Terms with Treatment
Table 1
Rett Syndrome (consensus criteria—2010) (typical or classic).
| Regression followed by recovery or stabilization | | Must fulfill all main criteria and all exclusion criteria | | Supportive criteria while present not required | |
| Main Criteria | Partial or complete loss of purposeful hand skills | | Partial or complete loss of spoken language | | Gait abnormalities: dyspraxic or absent | | Stereotypic hand movements | |
| Exclusion Criteria | Traumatic brain injury | | Neurometabolic disease | | Severe infection | | Very abnormal development in first 6 months of life | |
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