Unresponsiveness of Experimental Canine Leishmaniosis to a New Amphotericin B Formulation

Table 2

Clinicopathological scores recorded in dogs infected with L. infantum.

Parameter	Severity grade
	0	1	2
CBC
Hematocrit/hemoglobin	Normal	Mild anemia	Severe anemia
Leukocytes	Normal	Leukocytosis	Leukopenia
Platelets	Normal	—	Thrombocytopenia
Biochemical profile
Proteins	Normal	Proteinemia	—
Urea	Normal	Elevated	—
Creatinine	Normal	Elevated	—
Albumin/globulin ratio	Normal	Reduced	—
ALT	Normal	Elevated	—
Electrolytes
K^+, Na^+, and Cl^−	Normal	—	Increased
Urine
Urine specific gravity	Normal	Reduced	—
Proteins	Normal	100 mg/dL	≥500 mg/dL
Protein/creatinine ratio	Normal (<0.5)	>0.5 <2	>2