Illness Severity, Social and Cognitive Ability, and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (Recombinant Human IGF-1)

Figure 4

EEG parameters assessed before (T0) and after (T1) IGF-1 treatment. Alpha band desynchronisation is shown for those patients who were more anxious at baseline (a). The mean frequency of theta waves at C4-T4 (b) is also shown as is the mean amplitude of delta waves at T3-O1 (c). S1–10: treated subjects 1–10.

(a)

(b)

(c)