Synthesis, Characterization, and Bioactivity of Schiff Bases and Their Cd^𝟐+, Zn^𝟐+, Cu^𝟐+, and Ni^𝟐+ Complexes Derived from Chloroacetophenone Isomers with S-Benzyldithiocarbazate and the X-Ray Crystal Structure of S-Benzyl-β-N-(4-chlorophenyl)methylenedithiocarbazate

Table 9

Shows the minimum inhibitory concentration (MIC) of the compounds.

Compound	MIC (mg/mL)
	S. aureus	B. cereus	K. rhizophila	E. coli	P. aeruginosa	C. freundii
NS2	<6.25	<6.25	25	<6.25	50	<6.25
Zn(NS2)2	<6.25	<6.25	12.50	<6.25	<6.25	<6.25
Cd(NS2)2	<6.25	—	100	—	<6.25	—
Ni(NS2)2	—	100	100	—	—	—
Cu(NS2)2	—	—	—	—	—	—
NS4	—	—	—	—	—	12.50
Zn(NS4)2	—	—	—	—	—	50
Cd(NS4)2	—	—	<6.25	—	—	—
Ni(NS4)2	25	—	—	—	—	50
Cu(NS4)2	<6.25	—	—	—	—	<6.25
SBDTC	<6.25	<6.25	<6.25	<6.25	0.78*	<6.25
Streptomycin	0.001563*	0.000391*	>0.10*	0.0008*	0.004*	0.004*
Neomycin	N/A	1.10*	0.0039*	0.0064*	N/A	0.032*
Chloramphenicol	0.005*	0.01*	0.05*	0.004*	0.02*	0.002*

— refers to the absence of an MIC value for a certain compound as it was not investigated for its MIC due to its low activity. *refers to an MIC value that was obtained from the previous literature or experiments. N/A: (not available).