Synthesis and In Vitro Antitumor Activity of Two Mixed-Ligand Oxovanadium(IV) Complexes of Schiff Base and Phenanthroline

Table 4

Depolarization of mitochondrial membrane potential of the BEL-7402 cells treated with complexes 1 and 2 for 48 h.

Concentration; (μM)	Complex 1		Complex 2
	Mean value of green fluorescence intensity (𝑋  ± SD)	% of control	Mean value of; green fluorescence intensity (𝑋  ± SD)	% of control
Control	59.84 ± 0.21	100.00 ± 0.35	16.01 ± 0.09	99.99 ± 0.58
60	44.86 ± 3.99	74.96 ± 6.67	19.33 ± 2.66	120.78 ± 16.60
90	76.99 ± 3.06**	128.65 ± 5.11**	38.85 ± 1.35**	242.73 ± 8.41**
135	85.02 ± 1.37**	142.07 ± 2.28**	58.23 ± 0.50**	363.78 ± 3.13**

Data are the mean ± SD of at least three independent experiments. ^∗𝑃 < 0.05; ^∗∗𝑃 < 0.01. ^∗𝑃 < 0.05 versus the control, the difference was significant. ^∗∗𝑃 < 0.01 versus the control, the difference was markedly significant.