Synthesis, Spectral Characterization, and Antiproliferative Studies of Mixed Ligand Titanium Complexes of Adamantylamine

Table 5

Cytotoxic studies of titanium complexes on HeLa, C6 and CHO cancer cell lines as determined by MTT assay.

Complex	Cell line (Source)
	Hela (cervical)	C6 (Rat glioma)	CHO (Ovary)
	IC50 (µM)
Ti(ada)2(bpome)2	13	17.8	19.9
Ti(ada)2(dpme)2	74	69.8	16.1
Ti(ada)2(dach)2	20.4	21	16.6
Ti(ada)2(phen)2	11.1	22.1	21.5
Ti(ada)2(bzac)2	4.06	21.8	46.1
Adamantylamine	104.5	148	123
Camptothecin	6.2	6.4	6.4