Research Article
Axially Ligated Zirconium(IV) Tetraphenylporphyrin: Synthesis, Characterization, and Biological Activity
Table 6
In vitro antibacterial evaluation of free base porphyrin and the corresponding zirconium(IV) porphyrin complexes.
| PORPHYRIN
| K. pneumoniae | S. aureus | E. faecalis | A. denitrificans | B. cereus | M. luteus | B. subtilis | Campylobacter |
| | H2TPP | — | — | 1 | — | — | — | — | — | | Zr(TPP)(acac)(phO) | — | — | 1.25 | — | — | — | — | — | | Zr(TPP)(acac)(p-NH2phO) | — | — | — | 1.5 | — | — | — | — | | Zr(TPP)(acac)(p-ClphO) | — | — | — | — | — | — | — | 1.5 | | Zr(TPP)(acac)(p-OCH3phO) | — | — | — | 1 | — | — | — | — | | Zr(TPP)(acac)(-naphtholate) | 1 | 1.15 | 1.1 | 1.25 | 1.1 | 1.5 | 1.75 | 1 | | Zr(TPP)(acac)(p-NO2phO) | 2 | 1 | 1.5 | 1.5 | 1.2 | 1.4 | 2.5 | 1.5 | | Zr(TPP)(acac)(p-CH3phO) | 1 | 0.7 | 1.7 | — | 0.9 | — | 0.7 | 0.7 | | Zr(TPP)(acac)(o,p-Cl2phO) | — | — | — | 0.9 | — | — | — | 1.25 | | Zr(TPP)(acac)(o,p-(NO2)2phO) | — | 1.25 | 1.25 | — | — | 2 | — | 1.5 | | Control chloramphenicol | 2.5 | 2.1 | 1.4 | 2 | — | 2.25 | 2 | 2 |
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