Synthesis, Structural Characterization, and Biological Activity Studies of Ni(II) and Zn(II) Complexes

Table 6

MIC values of antimicrobial activity of ligands and their metal complexes (μg/mL).

Compound	Bacillus  subtilis	Staphylococcus  aureus	Proteus  vulgaris	Klebsiella  pneumoniae	Candida  albicans
HL1	—	—	—	—	—
HL2	80	80	80	80	80
HL3	—	—	—	—	—
HL4	—	—	—	—	—
[Ni(L1)2]	35	40	32	41	75
[Ni(L2)2]·H2O	70	80	65	85	—
[Ni(L3)2]·H2O	45	45	50	33	33
[Ni(L4)2]	75	80	—	78	—
[Zn(L1)2]·H2O	—	—	—	—	—
[Zn(L2)2]	85	78	80	75	80
[Zn(L3)2]	30	30	33	30	33
[Zn(L4)2]·H2O	—	80	—	80	—
Kanamycin	4	10	8	11	—
Clotrimazole	—	—	—	—	10