|
| Author | Study design | Sample size | Age | M/F | Change of TG | Severity | Replacement fluid | Anticoagulation | Mortality | Comments |
|
| Lennertz et al. [58] | Retrospective case series | 5 | 34 | 3/2 | -74% | NA | Albumin | Heparin bolus 5/5,
Heparin infusion 3/5,
Citrate 2/5 | 0 | Successful treatment of One pregnant patients |
|
| Chen et al. [44] | Retrospective comparison study | 60 (only 20 patints received PEX) | 42 ± 9 | NA | -66% | Ranson score >3 in 10 patients | FFP (8) and albumin (12) | Heparin | 4 | No mortality benefit of PEX as compared to conservative treatment, no insulin described in control group |
|
| Yeh et al. [59] | Case series | 18 | 27-65 | 13/5 | -66% | NA | Albumin | Heparin | 0 | PEX better in lowering TG as compared to double filtration |
|
| Yeh et al. [60] | Retrospective study | 17 | 31-53 | 10/7 | -66% | Ranson score 2 | FFP (8)/Albumin (9) | Heparin | 2 | Initiation of treatment at 3 days of symptoms onset, Anaphylactoid shock in one patient, 89% reduction in lipase levels |
|
| Kadikoylu et al. [61] | Case series | 7 | 47±3 | 5/2 | -46% | Asymptomatic | Albumin | Citrate | 0 | Asymtpomatic patients without any history of acute pancreatitis |
|
| Kyriakidis et al. [62] | Retrospective | 10 | 42 | 8/2 | -81% | Apache II 13 | FFP | Citrate | 1 | |
|
| Al-Humoud et a [63] | Retrospective case series | 8 | 34±9.19 | 6/2 | -67% | NA | Albumin | Heparin | 0 | |
|
| Gubenšek et al [49] | Retrospective case series | 50 | 45±8 | 46/4 | -80% | APACHE II 5 | Albumin | Heparin | 6 | 42% mortality in patients with APACHE II score ≥ 8, |
|
| Stefanutii et al [46] | Retrospective multicenter case series | 17 | 46 ± 10 | 9/8 | -61% | NA/Resistant to conservative therapy | Albumin | Heparin bolus followed by Citrate infusion | 0 | 12/17 patients had history of acute pancreatitis |
|
| Syed et al [64] | Retrospective case series | 4 | 36 | 3/1 | -89% | Apache II score 8 | Albumin | NA | 0 | Fast lowering of TG but no clinical improvement |
|
| Ramírez-Bueno et al. [20] | Retrospective case series | 11 | 40 ± 8 | 6/5 | -81% | APACHE II Score 13 (9-18) | Albumin | NA | 3 | All 3 patients who died had APACHE II score > 15, Low TG levels in patients with severe pancreatitis |
|
| Gubenesek et al. [19] | Retrospective observational cohort study | 111 | 47 ± 9 | 97/14 | -59% | 4 (2-7) | Albumin | Citrate (72) and Heparin (37) | 6 | 5 cases of hypotension and 5 cases of hypocalcemia with citrate anticoagulation, no difference between early and late plasmapheresis, better outcomes with citrate vs heparin group |
|
