Research Article
Novel Target Study to Cure Cardiovascular Disease regarding Proprotein Converse Subtilisin/Kexin Type 9
| | Number | ZINC ID | Rat NTPa | Mouse NTPa | AMESb | DTPc | | Male | Female | Male | Female |
| | 1 | ZINC000062238222 | 0.969 | 0.000 | 0.000 | 0.000 | 0.989 | 1.000 | | 2 | ZINC000085544839 | 0.964 | 0.000 | 0.080 | 0.000 | 0.999 | 1.000 | | 3 | ZINC000095620524 | 0.999 | 1.000 | 0.000 | 1.000 | 0.000 | 1.000 | | 4 | ZINC000004099069 | 0.000 | 0.000 | 0.000 | 0.000 | 0.002 | 0.864 | | 5 | ZINC000004654845 | 0.000 | 1.000 | 1.000 | 0.000 | 1.000 | 1.000 | | 6 | ZINC000085541163 | 0.998 | 1.000 | 1.000 | 0.186 | 0.000 | 1.000 | | 7 | ZINC000008552069 | 0.997 | 0.000 | 0.000 | 0.015 | 1.000 | 1.000 | | 8 | ZINC000013513540 | 0.840 | 0.020 | 0.000 | 0.139 | 0.000 | 1.000 | | 9 | ZINC000004228293 | 1.000 | 0.000 | 0.000 | 0.165 | 0.000 | 1.000 | | 10 | ZINC000009212428 | 1.000 | 0.000 | 0.000 | 1.000 | 0.356 | 1.000 | | 11 | ZINC000014952116 | 0.000 | 0.000 | 0.000 | 0.001 | 0.000 | 0.928 | | 12 | ZINC000014712793 | 0.632 | 1.000 | 0.000 | 0.640 | 0.000 | 1.000 | | 13 | ZINC000011616636 | 1.000 | 1.000 | 1.000 | 0.000 | 1.000 | 1.000 | | 14 | ZINC000008220036 | 0.000 | 1.000 | 1.000 | 0.000 | 0.064 | 0.000 | | 15 | ZINC000004096653 | 0.000 | 1.000 | 1.000 | 0.000 | 1.000 | 1.000 | | 16 | ZINC000012494317 | 0.000 | 0.000 | 0.000 | 0.222 | 0.000 | 1.000 | | 17 | ZINC000014951658 | 0.000 | 1.000 | 0.000 | 1.000 | 0.000 | 1.000 | | 18 | ZINC000085826835 | 0.998 | 1.000 | 1.000 | 0.186 | 0.000 | 1.000 | | 19 | ZINC000042805482 | 0.998 | 1.000 | 1.000 | 0.186 | 0.000 | 1.000 | | 20 | ZINC000004097774 | 0.053 | 0.987 | 0.916 | 0.000 | 0.002 | 1.000 | | 21 | 6U3X | 1.000 | 0.139 | 0.012 | 0.002 | 1.000 | 1.000 |
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a0 (noncarcinogen) and 1 (carcinogen); b0 (nonmutagen) and 1 (mutagen); c0 (nontoxic) and 1 (toxic).
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