Research Article
Development of a Novel Vaccine Candidates against Cardiobacterium valvarum through Reverse Vaccinology and Computational Approaches
Table 5
Net binding-free energy calculation.
| | Energy parameter | TLR-4 and vaccine | MHC-I- and vaccine | MHC-II-and vaccine |
| | MM-GBSA | | | | | VDWAALS | -78.00 | -60.00 | -65.00 | | EEL | -45.00 | -39.00 | -31.00 | | Delta G gas | -123 | -99 | -96 | | Delta G solv | 29.00 | 21.00 | 20.00 | | Delta total | -94 | -78 | -76 | | MM-PBSA | | | | | VDWAALS | -78.00 | -60.00 | -65.00 | | EEL | -45.00 | -39.00 | -31.00 | | Delta G gas | -123 | -99 | -96 | | Delta G solv | 26.00 | 38.00 | 24.00 | | Delta total | -97 | -61 | -72 |
|
|
