An In Silico Cardiomyocyte Reveals the Impact of Changes in CaMKII Signalling on Cardiomyocyte Contraction Kinetics in Hypertrophic Cardiomyopathy
Figure 2
transients recorded from control and HCM cardiomyocytes input into the multifilament half-sarcomere model. (a) Transients recorded in current clamp mode from a study on 26 HCM patients [17]. (b) Transients recorded from a study on 96 patients with a MYBPC3 mutation [19].