Synthesis, Spectral Characterization, and Biochemical Evaluation of Antidiabetic Properties of a New Zinc-Diosmin Complex Studied in High Fat Diet Fed-Low Dose Streptozotocin Induced Experimental Type 2 Diabetes in Rats

Table 1

The levels of blood glucose, glycosylated hemoglobin (HbA1c), plasma insulin, and urine sugar in control and experimental groups of rats.

Groups	Blood glucose	HbA1c	Insulin	C-peptide	Urine sugar
Control	95.75 ± 6.04	4.51 ± 0.29	15.41 ± 0.27	0.25 ± 0.023	Nil
Diabetic control	268.16 ± 9.97	10.87 ± 0.43	10.28 ± 0.43	0.11 ± 0.007	+++
Diabetic + Zn-diosmin	118.69 ± 4.57	6.23 ± 0.32	13.07 ± 0.55	0.17 ± 0.010	Nil
Diabetic + metformin	109.47 ± 5.40	5.79 ± 0.97	13.82 ± 0.47	0.19 ± 0.012	Nil

Units are expressed as mg/dL for blood glucose, % hemoglobin for HbA1c, U/mL for plasma insulin, and pmol/mL for plasma C-peptide; +++ indicates more than 2% sugar.
Results are expressed as mean ± SEM []. One-way ANOVA followed by post hoc test LSD was done. Values are statistically significant at ; . The results were compared to control rats and compared to diabetic rats.