Synthesis, Spectral Characterization, and Biochemical Evaluation of Antidiabetic Properties of a New Zinc-Diosmin Complex Studied in High Fat Diet Fed-Low Dose Streptozotocin Induced Experimental Type 2 Diabetes in Rats

Table 4

Effect of Zn-diosmin complex on levels of activities of AST, ALT, and ALP in the serum of control and experimental groups of rats.

Groups	AST	ALT	ALP
Control	71.06 ± 2.28	21.27 ± 0.63	72.45 ± 0.85
Diabetic control	131.72 ± 2.26	45.24 ± 1.64	149.09 ± 1.45
Diabetic + Zn-diosmin	83.94 ± 2.28	24.51 ± 1.01	93.85 ± 2.05
Diabetic + metformin	71.39 ± 1.90	21.14 ± 0.94	71.75 ± 1.74

Enzyme activities are expressed as AST and ALT – l moles of pyruvate liberated/h/mg of protein, ALP – l moles of phenol liberated/min/mg of protein.
Results are expressed as mean ± SEM []. One-way ANOVA followed by post hoc test LSD was done. Values are statistically significant at . The results were  compared to control rats and compared to diabetic rats.