Transcriptional Activation of p53 during Cold Induced Torpor in the 13-Lined Ground Squirrel Ictidomys tridecemlineatus

Figure 2

Expression of p53 upstream regulators in the ground squirrel skeletal muscle over six stages of the hibernation cycle. Relative protein expressions and Western blots are shown for (a) MDM2 protein, and (b) phosphorylated checkpoint kinase 1 (S296) and checkpoint kinase 2 (T68). Data show means ± SEM, -5 independent trials on tissues from different animals. denotes significant statistical difference from EC values, .

(a)

(b)