Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat’s Brain, Liver, and Kidney

Table 2

Effect of CAR on MDA (nmol/mgp), GSH (µmol/mgp), SOD (U/mgp), GPx (U/mgp), GR (U/mgp), and CAT (U/mgp) levels in brain of immobilization stress and control groups (, for each group).

Brain	MDA	GSH	SOD	GPx	GR	CAT
Veh-NS	2.68 ± 0.12	8.11 ± 0.40	3.12 ± 0.10	1.03 ± 0.15	0.85 ± 0.11	5.01 ± 0.35
Veh-S	6.28 ± 0.24	3.67 ± 0.15	0.98 ± 0.13	0.37 ± 0.10	0.29 ± 0.12	2.47 ± 0.11
CAR20-NS	2.23 ± 0.18	8.01 ± 0.39	3.06 ± 0.16	0.96 ± 0.13	0.93 ± 0.08	4.87 ± 0.18
CAR30-NS	2.41 ± 0.21	7.89 ± 0.45	2.92 ± 0.20	1.11 ± 0.12	0.87 ± 0.13	5.10 ± 0.15
CAR40-NS	2.36 ± 0.17	7.95 ± 0.48	3.23 ± 0.15	1.17 ± 0.10	0.90 ± 0.10	5.07 ± 0.21
CAR20-S	5.13 ± 0.25	4.02 ± 0.22	1.35 ± 0.28	0.55 ± 0.05	0.43 ± 0.09	2.93 ± 0.20
CAR30-S	3.98 ± 0.11	5.18 ± 0.29	2.07 ± 0.19	0.74 ± 0.09	0.52 ± 0.10	3.72 ± 0.13
CAR40-S	2.87 ± 0.19	7.26 ± 0.30	2.85 ± 0.24	0.96 ± 0.14	0.74 ± 0.05	4.57 ± 0.26

Each measurement was done at least in triplicate and the values are the means ± SEM for eight rats in each group.
Significantly different from Veh-NS groups (, ).
Significantly different from Veh-S groups (, , and ).
Significant difference in CAR20-S versus CAR30-S and CAR40-S groups (, ).
Significant difference in CAR30-S group versus CAR40-S group ().