Research Article

Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat’s Brain, Liver, and Kidney

Table 3

Effect of CAR on MDA (nmol/mgp), GSH (µmol/mgp), SOD (U/mgp), GPx (U/mgp), GR (U/mgp), and CAT (U/mgp) levels in liver of immobilization stress and control groups (, for each group).

LiverMDAGSHSODGPxGRCAT

Veh-NS 1.14 ± 0.25 10.09 ± 1.085.39 ± 0.651.04 ± 0.09 0.67 ± 0.11 6.09 ± 0.24
Veh-S 3.97 ± 0.164.56 ± 0.762.73 ± 0.390.45 ± 0.100.24 ± 0.092.98 ± 0.44
CAR20-NS 0.98 ± 0.109.81 ± 0.905.09 ± 0.781.01 ± 0.020.71 ± 0.035.87 ± 0.76
CAR30-NS 1.06 ± 0.1910.16 ± 1.065.12 ± 0.440.89 ± 0.060.60 ± 0.055.67 ± 0.81
CAR40-NS 1.20 ± 0.2110.00 ± 0.957.23 ± 0.271.12 ± 0.140.58 ± 0.076.12 ± 0.51
CAR20-S 3.01 ± 0.116.12 ± 1.113.01 ± 0.320.58 ± 0.030.42 ± 0.013.72 ± 0.38
CAR30-S 2.20 ± 0.147.46 ± 0.504.12 ± 0.500.69 ± 0.070.52 ± 0.134.53 ± 0.53
CAR40-S 1.58 ± 0.158.96 ± 1.095.06 ± 0.210.91 ± 0.130.61 ± 0.085.71 ± 0.32

Each measurement was done at least in triplicate and the values are the means ± SEM for eight rats in each group.
Significantly different from Veh-NS groups (, , and ).
Significantly different from Veh-S groups (, , and ).
Significant difference in CAR20-S group versus CAR20-S group (, ).