Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat’s Brain, Liver, and Kidney
Table 3
Effect of CAR on MDA (nmol/mgp), GSH (µmol/mgp), SOD (U/mgp), GPx (U/mgp), GR (U/mgp), and CAT (U/mgp) levels in liver of immobilization stress and control groups (, for each group).
Liver
MDA
GSH
SOD
GPx
GR
CAT
Veh-NS
1.14 ± 0.25
10.09 ± 1.08
5.39 ± 0.65
1.04 ± 0.09
0.67 ± 0.11
6.09 ± 0.24
Veh-S
3.97 ± 0.16
4.56 ± 0.76
2.73 ± 0.39
0.45 ± 0.10
0.24 ± 0.09
2.98 ± 0.44
CAR20-NS
0.98 ± 0.10
9.81 ± 0.90
5.09 ± 0.78
1.01 ± 0.02
0.71 ± 0.03
5.87 ± 0.76
CAR30-NS
1.06 ± 0.19
10.16 ± 1.06
5.12 ± 0.44
0.89 ± 0.06
0.60 ± 0.05
5.67 ± 0.81
CAR40-NS
1.20 ± 0.21
10.00 ± 0.95
7.23 ± 0.27
1.12 ± 0.14
0.58 ± 0.07
6.12 ± 0.51
CAR20-S
3.01 ± 0.11
6.12 ± 1.11
3.01 ± 0.32
0.58 ± 0.03
0.42 ± 0.01
3.72 ± 0.38
CAR30-S
2.20 ± 0.14
7.46 ± 0.50
4.12 ± 0.50
0.69 ± 0.07
0.52 ± 0.13
4.53 ± 0.53
CAR40-S
1.58 ± 0.15
8.96 ± 1.09
5.06 ± 0.21
0.91 ± 0.13
0.61 ± 0.08
5.71 ± 0.32
Each measurement was done at least in triplicate and the values are the means ± SEM for eight rats in each group. Significantly different from Veh-NS groups (, , and ). Significantly different from Veh-S groups (, , and ). Significant difference in CAR20-S group versus CAR20-S group (, ).