Research Article

Protective Effects of Carvacrol against Oxidative Stress Induced by Chronic Stress in Rat’s Brain, Liver, and Kidney

Table 4

Effect of CAR on MDA (nmol/mgp), GSH (µmol/mgp), SOD (U/mgp), GPx (U/mgp), GR (U/mgp), and CAT (U/mgp) levels in kidney of immobilization stress and control groups (, for each group).

KidneyMDAGSHSODGPxGRCAT

Veh-NS 1.79 ± 0.33 7.65 ± 0.364.12 ± 0.272.34 ± 0.15 1.88 ± 0.07 5.01 ± 0.24
Veh-S 4.08 ± 0.293.81 ± 0.412.51 ± 0.110.86 ± 0.121.02 ± 0.112.73 ± 0.11
CAR20-NS 1.67 ± 0.217.29 ± 0.284.01 ± 0.142.05 ± 0.10 1.68 ± 0.234.89 ± 0.31
CAR30-NS 1.83 ± 0.387.83 ± 0.473.87 ± 0.332.11 ± 0.23 1.93 ± 0.145.22 ± 0.42
CAR40-NS 1.74 ± 0.417.08 ± 0.324.28 ± 0.101.92 ± 0.272.03 ± 0.105.10 ± 0.23
CAR20-S 3.77 ± 0.25 4.65 ± 0.122.88 ± 0.201.02 ± 0.481.24 ± 0.052.65 ± 0.27
CAR30-S 2.90 ± 0.17 5.85 ± 0.223.43 ± 0.451.37 ± 0.261.36 ± 0.173.12 ± 0.51
CAR40-S 1.93 ± 0.466.88 ± 0.314.05 ± 0.192.25 ± 0.331.72 ± 0.164.55 ± 0.18

Each measurement was done at least in triplicate and the values are the means ± SEM for eight rats in each group.
Significantly different from Veh-NS groups (, ).
Significantly different from Veh-S groups (, , and ).
Significant difference in CAR20-S versus CAR30-S and CAR40-S groups (, , and ).
Significant difference in CAR30-S group versus CAR40-S group ().