Research Article
Tropomyosin Isoform Diversity in the Cynomolgus Monkey Heart and Skeletal Muscles Compared to Human Tissues
Table 2
Expression of transcripts of various sarcomeric TPMs in heart and skeletal muscles in human and nonhuman primate.
| | Isoform |
Human heart | Monkey heart | Human skeletal muscles | Monkey skeletal muscles |
| | TPM1α | 1.95 × 10^10 ± 1.94 × 10^7 | 1.60 × 10^10 ± 6.04 × 10^6 | 1.73 × 10^10 ± 4.70 × 10^6 | 2.72 × 10^10 ± 6.80 × 10^7 | | TPM1κ | 1.57 × 10^8 ± 5.30 × 10^5 | 7.01 × 10^6 ± 8.90 × 10^3 | 2.32 × 10^6 ± 2.80 × 10^3 | 7.65 × 10^5 ± 6.98 × 10^2 | | TPM2α | 1.40 × 107 ± 9.40 × 10^1 | 9.00 × 10^6 ± 6.20 × 10^4 | 5.50 × 10^8 ± 4.90 × 10 | 9.60 × 10^7 ± 4.50 × 10^5 | | TPM3α | 1.60 × 107 ± 3.20 × 103 | 1.40 × 10^6 ± 2.70 × 10^3 | 2.10 × 108 ± 1.90 × 10^4 | 5.26 × 10^7 ± 2.90 × 10^4 | | TPM4α | 7.70 × 10^3 ± 4.70 × 10 | 1.46 × 10^5 ± 1.50 × 10^2 | 1.03 × 10^4 ± 1.70 × 10 | 8.50 × 10^4 ± 4.00 × 10 |
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cDNA from human and Cyn RNA were made with the same oligonucleotide(s) and amplified with the same primer pair.
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