Research Article

Impact of Chronic Kidney Disease on Clinical Outcomes during Hospitalization and Five-Year Follow-Up after Coronary Artery Bypass Grafting

Table 5

Operative details and outcomes of the studied patients according to GFR.

Studied variablesPatients with GFR > 60Patients with early CKDPatients with late CKDPatients on dialysis value

Type of surgeryIsolated CABG (n, %)263 (90.1)67 (90.5)10 (83.3)30 (93.8)0.73
CABG plus valve surgery (n, %)30 (10.3)7 (9.5)1 (9.1)2 (6.3)
Cardiopulmonary bypass (minutes)100 (79–125)96 (75–128)120.5 (87–153)98 (73–110)0.28
Aortic clamping (minutes)63 (44.5–85)49.5 (40–77)62 (50–120)48 (41–75)0.07
ApproachSternotomy (n, %)286 (97.9)71 (95.9)10 (90.9)31 (96.9)0.28
Minimally invasive7 (2.4)3 (4.1)1 (9.1)1 (3.1)
Urgency of surgeryElective (n, %)282 (96.6)71 (95.9)11 (100)32 (100)0.8
Emergent (n, %)11 (3.8)3 (4.1)0 (0)0 (0)
Exploration for bleeding (n, %)21 (7.2)4 (5.4)0 (0)2 (6.3)0.97
New onset AF (n, %)78 (26.7)24 (32.4)2 (18.2)5 (15.6)0.3
Ventricular arrhythmias (n, %)16 (5.5)6 (8.1)1 (9.1)1 (3.1)0.61
Acute kidney injury (n, %)59 (20.2)36 (48.6)10 (90.9)0 (0)<0.001
New need for hemodialysis (n, %)7 (2.4)11 (14.9)5 (45.5)0 (0)<0.001
Gastrointestinal bleeding (n, %)11 (3.8)8 (10.8)1 (9.1)0 (0)0.044
Sternotomy wound infection (n, %)38 (13)11 (14.9)1 (9.1)3 (9.4)0.9
Wound debridement (n, %)23 (7.9)11 (14.9)1 (9.1)2 (6.3)0.28
ICU days4 (3–5)5 (3–7)12 (4–26)4 (3–5)0.002
Inotrope days1 (1-2)2 (1–4)4 (2–12)2 (1-2)<0.001
Ventilator days1 (1-1)1 (1-2)4 (1–18)1 (1-2)0.001
Post-ICU ward days4 (3–6)6 (3–11)7 (5–16)5 (4–7)0.006
Postoperative ECMO (n, %)5 (1.7)2 (2.7)1 (9.1)0 (0)0.27
Postoperative IABP (n, %)24 (8.2)6 (8.1)1 (9.1)1 (3.1)0.81
Tracheostomy (n, %)6 (2.1)4 (5.4)2 (18.2)0 (0)0.02
Hospital mortality (n, %)6 (2.1)3 (4.1)1 (9.1)1 (3.1)0.03
Hospital cerebrovascular stroke (n, %)19 (6.5)10 (13.5)2 (18.2)0 (0)0.03
Acute ischemic stroke (n, %)18 (6.2)10 (13.5)2 (18.2)0 (0)0.03
Acute intracerebral bleeding (n, %)1 (0.34)0 (0)0 (0)0 (0)1
Stroke during follow-up (n, %)7 (2.4)3 (4.1)1 (9.1)4 (12.5)0.028
Mortality during follow-up (n, %)16 (5.5)10 (13.5)0 (0)2 (6.3)0.104