Research Article

Inhibition of NF-κB by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ-Radiation Cytotoxicity in Glioblastoma Cells

Table 1

Doses required to induce 50% inhibition of cell growth (IC50) in GBM cell lines treated with DHMEQ and TMZ.

Cell lineIC50 values calculated at 48 hIC50 values calculated at 72 h
DHMEQ μg/mLTMZ μMDHMEQ μg/mLTMZ μM

U25121.78744.5113.50646.18
U343MG-a22.62570.1311.52508.14
U138MG1068.011315.3317.931170.32
U87MG35.061328.0614.45163.56
T98G28.194106.5318.621382.06
LN31922.621729.748.00897.31