Protective Effect of Quercetin on Melphalan-Induced Oxidative Stress and Impaired Renal and Hepatic Functions in Rat

Table 3

Protective effects of quercetin on melphalan-induced changes in the plasma activities of ALT, AST, ALP, and γ-GT in rats.

Treatment	ALT (U/L)	AST (U/L)	ALP (U/L)	γ-GT (U/L)
CTRL	21 ± 0.24	174 ± 2.30	257 ± 2.41	1.4 ± 0.16
MPLN	45 ± 1.22 (144.3%)^*	298 ± 3.32 (71.3%)^*	406 ± 2.61 (57.9%)^*	5.7 ± 0.28 (307.2%)^*
MPLN + QCT-P	34 ± 1.40^*†	204 ± 2.30^*†	319 ± 2.28^*†	4.5 ± 0.23^*†
MPLN + QCT-C	28 ± 0.56^*†	195 ± 3.87^*†	331 ± 2.28^*†	4.2 ± 0.25^*†
QCT-A	27 ± 0.74^*†	184 ± 1.59^*†	279 ± 2.28^*†	3.2 ± 0.19^*†

Data represent the means ± SD for five rats in each group; ^*significantly different from the CTRL; ^†significantly different from MPLN. Values in parenthesis represent percentage (%) increase.