Research Article

Protective Effect of Quercetin on Melphalan-Induced Oxidative Stress and Impaired Renal and Hepatic Functions in Rat

Table 4

Protective effect of quercetin on melphalan-induced changes in hepatic SOD and CAT activities in rats.

TreatmentSOD (Units)CAT (mole H2O2 consumed/min/mg protein)

CTRL8.38 ± 0.180.23 ± 0.02
MPLN5.5 ± 0.22 (34.4%)*0.11 ± 0.01 (52.2%)*
MPLN + QCT-P7.04 ± 0.17*†0.19 ± 0.01*†
MPLN + QCT-C7.48 ± 0.18*†0.18 ± 0.01*†
QCT-A7.84 ± 0.11*†0.22 ± 0.02*

Data represent the means ± SD for five rats in each group; *significantly different from the CTRL; significantly different from MPLN. Values in parenthesis represent percentage (%) decrease.