Research Article
Computational Modeling of Tumor Response to Vascular-Targeting Therapies—Part I: Validation
Table 2
Dosing Schedule for Simulated Drugs.
| Drug | Dosing Schedule | Therapeutic Levels? |
| AI | Once every two weeks | Maintained between successive treatments due to 20 day half-life of drug [43] |
| Cytotoxic Chemotherapeutic | Daily (up to 6 weeks in a row) | Maintained between successive treatments due to 1.8 hour half life of drug [44] |
| VDA | Once every three weeks | Maintained only in a 24 hour window after drug administration due to 4.2 hour half-life of drug [45] |
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