Lymphocyte-Rich Hepatocellular Carcinoma with Multiple Lymphadenopathy and Positive Epstein–Barr Virus Encoding Region

Figure 3

Pathological findings (original magnification, ×400): Immunohistochemical staining revealed positive AE1/AE3 (a) and positive GPC-3 (b) expression in the tumor cells. Hematoxylin and eosin staining exhibited small nests of pleomorphic tumor cells within a dense lymphoid stroma (c). The majority of lymphocytes stained positive for CD3 (d), while scattered lymphocytes showed positive staining for CD20 (e). Epstein–Barr virus encoding region in situ hybridization (EBER) demonstrated positive signals (f).

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