| | Author | Year | Age | Gender | Symptoms | Location | Size (cm) | Imaging | Tumor marker | Biopsy | Squamous transformation | Treatment | Outcome |
| | Dardik | 1964 | 69 | F | Abd pain, jaundice | R Lobe | 9 | | | Excision: diagnostic | Not present | Resection | | | Wheeler | 1984 | 69 | M | Asymptomatic | Ant seg R lobe | 2.5 | Unilocular | | Excision: diagnostic | Not present | Resection | | | Kadoya | 1990 | 41 | M | Asymptomatic | Seg 4 | 2 | Nonenhancing, hypoechoic (US), hypodense (CT), hypointense (SE 500/20). Hyperintense (SE 2500/25, SE 2500/80) | | Excision: diagnostic | Not present | Resection | | | Kadoya | 1990 | 56 | F | Asymptomatic | Seg 4 | 3 | Unilocular, nonenhancing, hypoechoic (US), hyperdense (CT) | | Excision: diagnostic | Not present | Resection | | | Kadoya | 1990 | 69 | M | Abd pain | Seg 4 | 2 | Nonenhancing, hypoechoic (US), hypodense (CT) | | FNA: non-diagnostic | Not present | | | | Partial wall: diagnostic | | Kimura | 1990 | 67 | M | Asymptomatic | Seg 4 | 3.5 | Unilocular, nonenhancing, hypoechoic (US), hyperdense (CT), hyperintense (T1, T2) | | Excision: diagnostic | Not present | Resection | Uncomplicated | | Abe | 1994 | 57 | M | Asymptomatic | Seg 4 | 1.9 | Unilocular, nonenhancing, hypoechoic (US), hypodense (CT), hypointense (T1), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | | | Zaman | 1995 | 35 | F | Asymptomatic | Seg 4 | 3 | Nonenhancing, hypodense (CT) | | FNA: diagnostic | Not present | | | | Carnicer | 1996 | 5 | F | Abd discomfort | Between portal vein & gallbladder | 2 | Unilocular, nonenhancing, hypoechoic (US), hypodense (CT), isointense (T1), hyperintense (T2) | | FNA: diagnostic | Not present | Observation | Resolved symptoms | | Hornstein | 1996 | 38 | M | Abd pain | Ant seg R lobe | 3 | Hypoechoic (US) | | FNA: diagnostic | Not present | Resection | | | Hornstein | 1996 | 53 | F | Asymptomatic | Ant seg R lobe | 3 | Hypodense (CT) | | FNA: diagnostic | Not present | | | | Hornstein | 1996 | 69 | M | Asymptomatic | Ant seg R lobe | 3.5 | Hypodense (CT) | | FNA: diagnostic | Not present | Resection | | | Murakami | 1996 | 63 | F | Asymptomatic | Seg 4 | 2.2 | Nonenhancing, hypoechoic (US), hyperdense (CT), hyperintense (T2) | Normal AFP. Elevated CEA, CA19-9 | FNA: non-diagnostic | Not present | Resection | | | Excision: diagnostic | | Harty | 1998 | 17 | F | Abd discomfort, jaundice, splenomegaly | R Lobe | 8 | Hypoechoic (US), hyperintense (T1, T2) | | | Squamous metaplasia | | | | Vick (a) | 1999 | 51 | M | Abd pain | R Lobe | 12 | | | Excision: diagnostic | SCC | Resection | Death | | Vick (b) | 1999 | 14 | F | Jaundice | | 6 | Multilocular | | | Not present | | | | Vick (b) | 1999 | 45 | M | Asymptomatic | Seg 4 | 3 | Unilocular | | | Not present | | | | Vick (b) | 1999 | 48 | M | Asymptomatic | R Lobe | | Unilocular | | | Not present | | | | Vick (b) | 1999 | 59 | F | Asymptomatic | | 3 | Unilocular | | | Not present | | | | Vick (b) | 1999 | 60 | F | Asymptomatic | | 1.1 | Unilocular | | | Not present | | | | Vick (b) | 1999 | 61 | M | Asymptomatic | Ant seg R lobe | 2.5 | Unilocular | | | Not present | | | | Kwak | 2000 | 69 | M | Asymptomatic | Seg 4 | 2.5 | Unilocular, nonenhancing, hypodense (CT) | | Excision: diagnostic | Not present | Resection | | | Hirata | 2001 | 53 | M | Asymptomatic | Seg 4 | 4 | Unilocular, nonenhancing, anechoic (US), hypodense (CT), hyperintense (T1, T2) | | FNA: non-diagnostic | Not present | | | | Excision: diagnostic | | Bogner | 2002 | 55 | M | Asymptomatic | R Lobe | 2.5 | | | Excision: diagnostic | Not present | Resection | | | Furlanetto | 2002 | 21 | M | Abd pain, weight loss | Seg 5, 6 | 10 | Polyseptated, hypoechoic (US), hypodense (CT) | Normal AFP, CEA, CA19-9 | FNA: non-diagnostic | SCC | Resection, chemotherapy | Death | | Excision: diagnostic | | Lajarte-Thirouard | 2002 | 40 | F | Abd pain | Seg 5 | 13 | Irregular posterior wall, nonenhancing, hypoechoic (US), hypodense (CT), hyperintense (T1, T2) | | Excision: diagnostic | SCC | Resection | | | Del Poggio | 2003 | 58 | F | Asymptomatic | Seg 4 | 2 | Unilocular, nonenhancing, hypoechoic with hyperechoic spots (US), hypodense (CT), hyperintense (T2) | | FNA: diagnostic | Not present | Observation | | | Jakowski | 2004 | 40 | F | Abd pain, N/V | Seg 4 | 2.1 | Unilocular, hypodense (CT), hypointense (T1), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | | | Momin | 2004 | 68 | F | Asymptomatic | Seg 2, 3 | 3.8 | Unilocular, nonenhancing, “solid appearing” (US), hypodense (CT), hypointense (MRV) | | Excision: diagnostic | Not present | Resection | | | Fang | 2005 | 30 | M | Abd discomfort | Seg 4 | 4 | Unilocular, nonenhancing, hypodense (CT), isointense (T1), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | | | Rodriguez | 2005 | 20 | F | Abd pain, anorexia | Gallbladder fossa | | Unilocular, hyperintense (T2) | | Excision: diagnostic | Not present | Resection | | | Kang | 2006 | 56 | M | Asymptomatic | Seg 4 | 4.5 | Unilocular, nonenhancing, hypodense (CT), hyperintense (T2) | Normal CEA, CA19-9 | | Not present | Resection | Uncomplicated | | Ben Mena | 2006 | 31 | F | Abd pain | Seg 4 | 6 | Unilocular, nonenhancing, hypoechoic (US), hyperdense (CT) | Normal AFP, CEA, CA19-9 | Excision: diagnostic | Squamous metaplasia | Resection | | | Straus | 2006 | 63 | M | Asymptomatic | Seg 4 | 1.5 | Nonenhancing, hyperdense (CT) | | Excision: diagnostic | Not present | Resection | Alive | | Stringer | 2006 | 0 | M | Abd distension | Seg 5, 8 | 10 | Unilocular, rim enhancing, hypoechoic (US), hypodense (CT), “cystic lesion” (MRI) | | Excision: diagnostic | Squamous metaplasia | Resection | L hepatic duct necrosis | | Kaplan | 2007 | 68 | M | Asymptomatic | Seg 4 | 3 | Unilocular, nonenhancing, hypoechoic (US), hypodense (CT), hyperintense (T1, T2) | Normal AFP. Elevated CA19-9 | FNA: diagnostic | Not present | | | | Young | 2007 | 16 | F | Abd pain, anorexia | Ant seg R lobe | 6 | Multilocular, hyperintense (T2) | | FNA: non-diagnostic | Not present | Resection | | | Excision: diagnostic | | Shaw | 2007 | 50 | F | Abd pain | Porta Hepatis | 8 | Unilocular, hypodense (CT), hyperintense (T2) | Normal CA19-9 | Excision: diagnostic | Not present | Resection | Uncomplicated | | Betalli | 2008 | 0 | F | Asymptomatic | Seg 4 | 5 | Unilocular, nonenhancing, hypoechoic (US), isointense (T1), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | | | Geramizadeh | 2008 | 25 | M | Abd pain | Seg 8 | 2.7 | Hypoechoic (US) | | | Not present | Resection | Uncomplicated | | Kiyochi | 2008 | 69 | F | Abd pain, jaundice | Seg 4 | 2.5 | Unilocular, rim enhancing, hypoechoic (US), hypodense (CT), hypointense (T1), hyperintense (T2) | Elevated CA19-9 | Excision: diagnostic | Not present | Resection | | | Sharma | 2008 | 28 | F | Asymptomatic | Seg 4 | 5 | Solid component, nonenhancing, hypoechoic (US), hypodense (CT), hyperintense (T1, T2) | Normal AFP, CEA, CA19-9 | Excision: diagnostic | Not present | Resection | | | Zhang | 2009 | 60 | F | Abd fullness | Seg 4 | 7 | Hypoechoic (US) | Normal AFP, CEA, CA19-9 | Excision: diagnostic | SCC | Resection | Uncomplicated | | Zaydfudim | 2010 | 17 | F | Abd pain, nausea | Seg 4 | 6.5 | Hypoechoic (US), hypodense (CT) | Normal AFP | Needle core: diagnostic | Not present | Resection | Uncomplicated | | Ambe | 2012 | 42 | M | Abd pain | Seg 4 | 7 | Unilocular, hypodense (CT) | | Excision: diagnostic | Not present | Resection | | | Feernandez-Acenero | 2012 | 35 | F | Abd pain | Seg IV, V | 7 | US, CT | CK-19+; CA 19−9+: EMA+; TTF-1+ | | | Resection | Alive | | Feernandez-Acenero | 2012 | 33 | M | Asymptomatic | Seg IV | 6.5 | US; hyperintense (MRI) | CK-19+; CA 19−9+: EMA+; TTF-1+ | | | Resection | Alive | | Khoddami | 2013 | 3.5 | M | Abd pain | Seg 4 | 3.7 | Nonenhancing, hypoechoic (US), hypodense (CT) | | Excision: diagnostic | Not present | Resection | | | Khoddami | 2013 | 3.5 | M | Asymptomatic | R Lobe | 3.6 | Nonenhancing, heterogeneous, hyperechoic (US), hypodense (CT) | | Excision: diagnostic | Squamous metaplasia | Resection | | | Wilson | 2013 | 34 | M | Asymptomatic | Seg 4, 5, 8 | 14 | Nonenhancing, hypodense (CT), hypointense and heterogeneous (MRI) | Normal AFP, CEA, CA19-9 | Excision: diagnostic | SCC | Resection, TACE, systemic chemotherapy after recurrence | Recurrence and metastasis | | Ben Ari | 2014 | 45 | M | Abd pain | Seg 4 | 6.2 | Multilocular, nonenhancing, hypoechoic (US), hypodense (CT) | Normal AFP, CEA, CA19-9 | FNA: diagnostic | Not present | Resection | | | Excision: diagnostic | | Saravanan | 2014 | 32 | F | Abd pain | Seg 8 | 10 | Nonenhancing, hypoechoic (US), hypodense (CT) | Normal CA19-9 | Excision: diagnostic | Not present | Resection | | | Bishop | 2015 | 42 | F | Abd discomfort | Porta Hepatis | 8 | Unilocular | Normal CEA, CA19-9 | Excision: diagnostic | Not present | Resection | | | Bishop | 2015 | 46 | F | Asymptomatic | R Liver | 1 | Unilocular | | Needle core: diagnostic | Not present | Observation | Alive | | Bishop | 2015 | 50 | F | Asymptomatic | | 10 | Unilocular | | Partial wall: diagnostic | Not present | Partial resection | Alive | | Bishop | 2015 | 58 | F | Asymptomatic | Seg 4 | 0.7 | Unilocular | | Excision: diagnostic | Not present | Resection | | | Bishop | 2015 | 66 | M | Abd pain, N/V, jaundice | Seg 4 | 17 | Unilocular | Normal CEA. Elevated CA19-9 | Excision: diagnostic | Not present | Resection | | | Bishop | 2015 | 67 | M | Asymptomatic | Porta hepatis | 6.5 | Unilocular | Normal CEA, CA19-9 | Excision: diagnostic | Not present | Resection | Alive | | Bruns | 2015 | 4 | M | Asymptomatic | Seg 7 | 7.4 | Hypoechoic (US), hyperintense with enhancing septations (T2) | Normal AFP | Excision: diagnostic | Not present | Resection | Uncomplicated | | Grizzi | 2015 | 33 | M | Asymptomatic | L Lobe | 6.5 | Hypoechoic (US), hyperintense (T2) | | | Not present | Resection | | | Grizzi | 2015 | 35 | F | Abd discomfort | Seg 4, 5 | 7 | Hypoechoic (US), hypodense (CT) | | | Not present | Resection | | | Grizzi | 2015 | 45 | M | Abd pain | Seg 4 | 2 | Hypoechoic (US) | | | Not present | Resection | | | Grizzi | 2015 | 63 | F | Asymptomatic | | | Unilocular, hypodense (CT) | | | Not present | Resection | | | Beteddini | 2016 | 33 | F | Abd pain, vomiting | Triangle of Calot | 1.5 | Unilocular | | Excision: diagnostic | Not present | Resection | | | Cottreau | 2016 | 57 | F | Abd pain, jaundice | Common hepatic duct | 1.7 | Unilocular, hypoechoic (US), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | Uncomplicated | | Ansari-Gilani† | 2017 | 52 | M | Abd pain | Seg 4 | 2 | Hypodense (CT), hyperintense (T2) | | Unspecified | Not present | | | | Ansari-Gilani† | 2017 | 62 | F | Asymptomatic | Seg 4 | 1.5 | Nonenhancing, hypodense (CT), hyperintense (T1) | | Unspecified | Not present | | | | Ansari-Gilani† | 2017 | 68 | M | Asymptomatic | Seg 4 | | Nonenhancing, hypodense (CT), hyperintense (T1, T2) | | Unspecified | Not present | | | | Enke | 2019 | 54 | M | Asymptomatic | Seg 4 | 2.7 | Solid component, nonenhancing, hypodense (CT), hyperintense (T2) | | Excision: diagnostic | Not present | Resection | Uncomplicated | | Itose | 2020 | 50 | F | Abd pain | Seg 4 | 4 | Solid component, calcification, hypodense (CT) | Normal AFP, CEA. Elevated CA19-9 | Excision: diagnostic | SCC | Resection, chemotherapy | Recurrence and metastasis; alive at 30 months | | Ziogas | 2020 | 39 | M | Incidental | 4B | 2.5 | Unilocular | | | | Lap wedge resection/cyst unroofing | 1 LOS | | Ziogas | 2020 | 73 | F | Incidental | 7 | 2.9 | Unilocular | | | | Wedge resection | 4 LOS | | Ziogas | 2020 | 64 | F | Incidental | 4A | 2 | Unilocular | | | | Central Liver wedge resection | 7 LOS | | Ziogas | 2020 | 49 | M | Incidental | 4B | 2.5 | Unilocular | | | | Lap wedge resection | 2 LOS | | Ziogas | 2020 | 61 | F | Incidental | 4A | 2.4 | Unilocular | | | | Rob wedge resection | 3 LOS | | Ziogas | 2020 | 17 | M | Incidental | 4A | 1.5 | Unilocular | | | | Lap wedge resection/cyst unroofing | 0 LOS | | Ziogas | 2020 | 63 | M | Epigastric pain | 4A | 2 | Unilocular | | | | Lap wedge resection | 2 LOS | | Ziogas | 2020 | 62 | M | Incidental | Falciform ligament | 0.8 | Unilocular | | | | Lap wedge resection | 2 LOS | | Ziogas | 2020 | 58 | M | Incidental | 4A | 3 | Multilocular | | | | Lap wedge resection/cyst unroofing | 1 LOS | | Ziogas | 2020 | 47 | M | Incidental | 4 | 1.3 | Unilocular | | | | Lap wedge resection | 1 LOS | | Ziogas | 2020 | 67 | M | Incidental | Falciform ligament | 2 | Unilocular | | | | Hepatectomy for liver transplant | 83 LOS | | Ziogas | 2020 | 79 | M | Abd pain (lower) | 4 | 3 | Unilocular | | | | Wedge resection | 18 LOS | | Ziogas | 2020 | 78 | M | Abd pain (right side) | 4A-8 | 3.5 | Unilocular | | | | Wedge resection/cyst unroofing | 110 LOS | | Seyed-alagheband | 2023 | 41 | F | Abd pain; palpable mass | Seg 4 | 130 | Subhepatic cyst with internal septations (US and CT) | Normal LFTs | No | Not present | Lap resection | Uncomplicated 1.5 years | | Kato | 2023 | 75 | M | Asymptomatic | Seg 4 | 2.6 | Unilocular, nonenhancing, hypodense (CT) | Normal AFP. Elevated CEA | Excision: diagnostic | Not present | Resection | Uncomplicated |
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