Case Report
Pulmonary Limited MPO-ANCA Microscopic Polyangiitis and Idiopathic Lung Fibrosis in a Patient with a Diagnosis of IgA Nephropathy
Table 1
Change of p-ANCA, MPO, spirometry, and CT scanning characteristics in the period from December 2011 to October 2012.
| | | Period | | | December 2011 | June 2012 | October 2012 (after 5 cycles of cyclophosphamide) |
| | p-ANCA | 1/180 | 1/640 | 1/320 | | MPO (IU/L) | 45 | >1341 | 44 | | Spirometry | | | | | FVC (forced vital capacity) (liters) | 2.51 (58% of PV2) | 0.84 (20% of PV) | 2.23 (52% of PV) | | Forced expiratory volume 1 second (FEV1) (liters) | 1.99
(61% of PV) | 0.71
(22% of PV) | 1.63
(50% of PV) | | FEC/FVC % | 79 (74% of PV) | 84% (74% of PV) | 73% (74% of PV) | | VC (vital capacity) (liters) | 2.51 (56% of PV) | 0.98 (22% of PV) | 2.23 (50% of PV) | | TLC (total lung capacity) (liters) | 3.84 (51% of PV) | Not measured | 3.96 (53% of PV) | | RV (residual volume) (liters) | 1.33 (49% of PV) | Not measured | 1.73 (63% of PV) | | DLCO (diffusing capacity of the lung for carbon monoxide) (mL/mmHg/min) | 9.2
(32% of PV) | Not measured | 7.6
(27% of PV) | | CT scanning | Interstitial pneumonia/idiopathic lung fibrosis | Interstitial pneumonia/idiopathic lung fibrosis | Unchanged
(permanent damage) |
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Protocolled as >134 IU (above upper limit of test range).
PV: Predicted Value.
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