Tuberous Sclerosis and Bilateral Renal Angiomyolipomas: A Case Report and Literature Review of Emerging Treatment Strategies

Table 2

Table of PI3K, AKT, and mTOR inhibitors in development [4].

PI3K/AKT/mTOR pathway inhibitors
PI3K	AKT	mTOR
AZD6482	A-443654	AZD-8055
AR245408 (XL 147)	AR-42	BGT226
BAY 80-6946	AR-67 (DB-67)	Everolimus
BKM120	AZD5363	INK-128
BYL719	GSK690693	NVP-BEZ235
GDC-0941	KP372-1	ONC-01910
GDC-0980	MK-2206	OSI-027
GSK2636771	SR13668	PP-242
PF-04691502	Triciribine (API-2)	Rapamycin (sirolimus)
PX-866	VIII	Ridaforolimus
ONC-01910	VQD-002 (API-2)	Temsirolimus
		WYE-354