Case Report

Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma

Table 1

Laboratory findings.

UrinalysisBlood chemistry tests (cont.)

Gravity1.009Sodium136 mmol/L
Protein3+Chloride104 mmol/L
SugarNegativePotassium3.0 mmol/L
Blood1+Corrected calcium10.0 mg/dL
SedimentPhosphate3.0 mg/dL
Red blood cells5–9/HPFTotal bilirubin0.3 mg/dL
White blood cells10–19/HPFAspartate aminotransferase22 U/L
Urinary biochemical testsAlanine aminotransferase26 U/L
Daily urinary protein4.3 g/24 hrLactate dehydrogenase292 U/L
Selectivity index0.09Alkaline phosphatase167 U/L
Bence-Jones proteinNegativeCreatine kinase73 U/L
Complete blood countTotal cholesterol197 mg/dL
White blood cells10600/mLLDL cholesterol129 mg/dL
Neutrophils58%Triglyceride191 mg/dL
Eosinophils12%Glucose103 mg/dL
Basophils3%Hemoglobin A1c5.1%
Lymphocytes15%Serology
Monocytes11%C-reactive protein3.38 mg/dL
Hemoglobin11.0 g/dLHBs antigenNegative
Platelets57.3 × 104/mLAnti-HCV antibodyNegative
Coagulation testsImmunoglobulin G2288 mg/dL
PT-INR1.13Immunoglobulin A455 mg/dL
APTT28.5 secImmunoglobulin M94 mg/dL
APTT, ctrl33.5 secComplement 3170 mg/dL
Fibrinogen760 mg/dLComplement 417 mg/dL
von Willebrand factor341% (60–170%)CH5057.0 U/mL
Blood chemistry testsRheumatoid factor33 IU/mL
Total protein7.2 g/dLAntinuclear antibodyx40 >
Albumin2.4 g/dLAnti-dsDNA-Ab< 10 U/mL
Uric acid10.1 mg/dLPR3-ANCA< 1.0 U/mL
Urea nitrogen14.2 mg/dLMPO-ANCA< 1.0 U/mL
Creatinine1.59 mg/dLCryoglobulin(+)

HPF: high-power field; PT-INR: prothrombin time-international normalized ratio; APTT: activated partial thromboplastin time; CH50:50% hemolytic unit of complement; LDL: low-density lipoprotein; HBs: hepatitis B surface; HCV: hepatitis C virus; dsDNA-Ab: double-strand deoxyribonucleic acid antibody; PR3-ANCA: proteinase-3-antineutrophil cytoplasmic antibodies; MPO-ANCA: myeloperoxidase-antineutrophil cytoplasmic antibodies.