Case Report
Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma
Table 2
The literature review of cryoglobulin and renal diseases in malignant mesothelioma.
| | First Author | Year | Disease site | Complement | Cryoglobulin | Chemotherapy for mesothelioma | Renal Pathology |
| | Schroeter | 1986 | Pleura | Normal | NA | Cyclophosphamide, doxorubicin, hydrochloride, and decarbonize | MCNS | | Venzano | 1990 | Pleura | NA | NA | NA | MCNS | | Absy | 1992 | Pleura | NA | NA | Carboplatin | FSGS | | Tanaka | 1994 | Pleura | Normal | NA | Carboplatin, etoposide | MesPGN | | Galesic | 2000 | Pleura | Normal | NA | None (corticosteroid) | MN | | Sakamoto | 2000 | Pleura | NA | NA | None (surgery) | MN | | Farmer | 2001 | Pleura and brain metastasis | NA | NA | None (corticosteroid) | MCNS | | Bacchetta | 2009 | Testis | Normal | NA | Cisplatin and pemetrexed | MCNS | | Li | 2010 | Pleura | Normal | NA | Gemcitabine and carboplatin | MCNS | | Dogan | 2012 | Pleura | NA | NA | None (surgery) | Not examined | | Suzuki | 2014 | Pleura | Normal | NA | None (conservative) | MCNS | | Tsukamoto | 2015 | Pleura, pulmonary, and skull metastasis | NA | NA | Carboplatin, pemetrexed, and gemcitabine | MCNS | | Pu | 2016 | Pleura | NA | NA | Cisplatin and pemetrexed | MN | | Bickel | 2016 | Pleura | NA | NA | Carboplatin, pemetrexed, vinorelbine, and pembrolizumab | MCNS | | Yildiz | 2016 | Pleura | Normal | NA | None (corticosteroid) | MCNS | | Nagai | Present case | Pleural mesothelioma and bone metastasis | Low C4 | Positive | Cisplatin, pemetrexed, carboplatin, nivolumab, gemcitabine, and vinorelbine | Not examined |
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MCNS: minimal-change nephrotic syndrome; FSGS: focal segmental glomerulosclerosis; MesPGN: mesangial proliferative glomerulonephritis: MN: membranous nephropathy.
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