A Case of Syphilis Suspected Preoperatively as a Case of Tongue Cancer

Figure 2

Pathological findings. (a) Hematoxylin and eosin staining of the tongue lesion. Reactive nuclear enlargement of the epithelial cells is seen, accompanied by neutrophilic infiltration of the epithelium and plasma cells into the subepithelial layer. No evidence of malignancy was detected. Scale bar = 200 μm. (b) Immunohistochemical staining of the tongue lesion for Treponema pallidum (TP). Numerous spirochetes are seen within the epithelium. Scale bar = 100 μm. (c) Hematoxylin and eosin staining of the suspected metastatic lymph node. Epithelioid cell granulomas with necrosis at the center of fibrotic changes are observed. Scale bar = 100 μm. (d) Immunohistochemical stain of the lymph node for TP: multiple spirochetes are seen. Scale bar = 50 μm.

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