Case Report

Unusual Bladder Metastasis from a Primary Gastric Carcinoma: Two Case Reports and Review of Literature

Table 1

Review of urinary bladder metastasis from a primary gastric tumor reported in English language literature.

Author and yearAgeGenderPrimary gastric tumor stageClinical presentationHaematuriaInterval between primary tumor and metastasisImaging findingsPresence of hydronephrosisOther metastasisEndoscopic findingsManagement of bladder metastasisFollow-up

Saba et al. 1997 [7]58MSRC
AC
NilYes7 years HCPolypoid lesion in the bladder posterior wallNoRetroperitoneal adenopathyLarge broad-based lesion at the posterior wall, with mucinous strandsNilDeceased days after diagnosis
Kim et al. 2000 [4]60MACSense of residual urine dysuria, non-tender supra-pubic massMicroscopicOne year HCFocal thickening of the bladder anterior wallNoNilNRTURNR
Kim et al. 2000 [4]57FSRC
AC
Frequency, dysuriaMicroscopicFifteen months HCDiffuse bladder wall thickeningNoNilBullous oedema of the bladder mucosaTURNR
Kim et al. 2000 [4]42MSRC
AC
DysuriaMicroscopicTwo years HCDiffuse thickening of the bladder wallNoNilOedematous mucosa of the bladder with a small ulcerTotal cystectomyNR
Antunes et al. 2004 [8]63FACLeft lumbar pain, dysuria low abdominal painNilOne year and nine monthsThickened wall of the bladderBilateralAscitesExtensive vegetative lesion in the bladderTURStable condition 8 months after diagnosis
Matsuhashi et al. 2005 [9]90FTubular ACNausea, dysphagiaYeSynchronous metastasisThickening of the bladder wall with diverticulum enhance effectNoNilLesion in the bladder diverticulumNILDeceased three months after diagnosis
Farhat et al. 2007 [10]58MACNilYesFifteen months HC2 cm mass involving the trigone and the left lateral bladder wallNoNilNRTURNR
Sharma et al. 2011 [6]30MSRC
AC
Weight lossYesTwo years HCLocalized thickening of the bladder wallNoNilMultiple grape-like lesions on the dome and left bladderTUR adjuvant chemotherapyAlive five months after chemo
Andras et al. 2013 [11]59MTubular ACLow abdominal painNilTen years HC cm tumor-like mass on the left posterior bladder wallNoNilMucosal hyperaemia lesion close to the ureteric orificeTUR adjuvant chemotherapyColic recurrence one year after chemo
Kalra et al. 2015 [12]60MSRC
AC
Low urinary tract storage symptomsMicroscopicSynchronous metastasisDiffusely thickened bladder wall with small capacity bladderBilateralNilSmooth wall diffusely erythematous small capacity bladderTUR nephrostomy diversion
Palliative chemotherapy
Okutur et al. 2015 [13]48MSRC
AC
Abdominal pain, weight loss tenderness of hypogastric regionYesSynchronous metastasisDiffuse thickening of the bladder wallBilateralPeritoneumDiffuse papillary nodular lesionTransurethral biopsy
Palliative chemotherapy
Alive 5 months after chemotherapy
Lodh et al. 2016 [14]53MTubular ACAbdominal fullness weight lossYesSynchronous metastasisRight posterior lateral urinary bladder broad base massNoNilProtuberant massTUR adjuvant chemotherapyStable three month later
Vigliar et al. 2013 [15]38MSRC
AC
Abdominal painYesSeven months HCNRUnilateralAscitesNRNILDeceased nine months after diagnosis
Seow-En et al. 2015 [16]75MSRC
AC
FrequencyNilTwenty years HCBladder wall thickeningBilateralLymphadenopathy rectumMucosal tumor growthChemotherapyAlive four months since diagnosis
Khoury et al. 2019 [17]75MSRC
AC
Appetite loss, lumbar painNilTwo yearsDiffuse thickening of bladder wallBilateralNILExtensive vegetative lesionNRNR
Ota et al. 1999 [18]43MACSense of residual urine, incontinenceNilTwo years HCDiffuse thickening of bladder wallBilateralNilNRChemotherapyAlive twelve months after chemotherapy

SRC: signet ring cell; AC: adenocarcinoma; TUR: transurethral resection; HC: heterochronous; NR: not reported.