Metastatic Urothelial Carcinoma from Transplanted Kidney with Complete Response to an Immune Checkpoint Inhibitor

Figure 1

(a) The nephrectomy specimen demonstrated infiltrative nests of tumor cells with prominent nucleoli, moderate pleomorphism, and scattered mitoses (H&E). (b) Nuclear expression for p63 in the tumor cells supports the diagnosis of urothelial carcinoma. (c) SV40/BKV stain showing positive staining in the tumor cells. (d) PAX8 is negative in tumor cells, excluding renal cell carcinoma.

(a)

(b)

(c)

(d)