Research Article

The Localization and Characterization of Ischemic Scars in relation to the Infarct Related Coronary Artery Assessed by Cardiac Magnetic Resonance and a Novel Automatic Postprocessing Method

Table 2

Cardiac magnetic resonance characteristics assessed one year following acute myocardial infarction treated by primary percutaneous coronary intervention.

TotalInfarct related artery (IRA)
LAD ()RCA ()LCX ()

LGE-CMR data
 LVEF (%)52 ± 1147 ± 1156 ± 1053 ± 50.130
 LVEDVi (mL/m2)92 ± 2398 ± 2491 ± 2375 ± 110.120
 LVESVi (mL/m2)46 ± 2153 ± 2442 ± 1935 ± 60.110
 Scar size as %LV analyzed7.8 ± 5.59.5 ± 6.35.8 ± 4.38.7 ± 5.20.137
 Mean scar (pixels)113 ± 77118 ± 84107 ± 78116 ± 630.882
 Mean Δϕ44 ± 26°49 ± 31°37 ± 22°46 ± 17°0.571
 Endocardial extent as %LV circumference12.1 ± 7.2%13.6 ± 8.6%10.4 ± 6.2%12.9 ± 4.8%0.571
 Mean Δλ52 ± 20%52 ±  0.18%52 ± 0.24%56 ± 0.15%0.959
 Ratio scar area/sector with scar0.42 ± 0.140.45 ± 0.150.38 ± 0.120.46 ± 0.190.337
Manual data
 Scar as %LV analyzed17.4 ± 8.619.2 ± 11.215.2 ± 6.318.4 ± 1.00.506
 Mean Δϕ124 ± 47°154 ± 53°101 ±25°101 ± 11°0.006
 Endocardial extent of infarction as %LV circumference34.6 ± 13.042.9 ± 14.728.0 ± 6.828.0 ± 3.20.006
 Mean Δλ77 ± 23%83 ± 17%78 ± 19%58 ± 14%0.065

Kruskal-Wallis. Mann-Whitney test significant for the difference of mean Δϕ and endocardial extent of infarction as %LV circumference values of patients with LAD and RCA as IRA ( = 0.006 and = 0.002, resp.). LAD = left anterior descending artery. RCA = right coronary artery. LCX = left circumflex artery. LVEF = left ventricular (LV) ejection fraction. LVEDVi = LV end-diastolic volume index. LVESVi = LV end-systolic volume index. Δϕ = endocardium extent of infarction as angle. Δλ = transmurality of the scar as % of LV thickness.