Clinical Study

RyR2 QQ2958 Genotype and Risk of Malignant Ventricular Arrhythmias

Table 3

Genotypic frequency of the two analyzed polymorphisms in the study population and according to arrhythmias occurrence.

TotalGroup IGroup II value

RyR2 Q2958R (A>G) ()
 QQ 18 (7.7%)14 (13.9%)4 (3.0%)0.0040
 QR 213 (90.6%)85 (84.2%)128 (95.5%)
 RR 4 (1.7%)2 (1.9%)2 (1.5%)
HRC S96A (G>T) ()
 SS 38 (16.2%)12 (11.9%)26 (19.4%)0.1750
 SA 145 (61.7%)69 (68.3%)76 (56.7%)
 AA 52 (22.1%)20 (19.8%)32 (23.9%)

with Fisher’s exact test, while using Armitage trend test.