Clinical Study

RyR2 QQ2958 Genotype and Risk of Malignant Ventricular Arrhythmias

Table 5

Genotypic frequency of RyR2 Q2958R in the study population subgroups according to arrhythmias occurrence.

Group IGroup II value

Hypertensive patients ()
 QQ 12 (24.0%) 0 (0%) 0.0001
 QR 37 (74.0%) 56 (98.2%)
 RR 1 (2.0%) 1 (1.8%)
Not hypertensive patients ()
 QQ 2 (4.3%) 3 (4.2%) 1
 QR 43 (93.5%) 68 (94.4%)
 RR 1 (2.2%) 1 (1.4%)
Dyslipidemic patients ()
 QQ5 (11.9%)6 (11.1%)1
 QR36 (85.7%)47 (87.0%)
 RR1 (2.4%)1 (1.9%)
Not dyslipidemic patients ()
 QQ4 (7.4%)3 (4.0%)0.6777
 QR49 (90.8%)71 (94.7%)
 RR1 (1.8%)1 (1.3%)
Diabetic patients ()
 QQ 6 (15.0%) 2 (4.0%) 0.0696
 QR 33 (82.5%) 48 (96.0%)
 RR 1 (2.5%) 0 (0%)
Not diabetic patients ()
 QQ8 (14.3%) 2 (2.5%) 0.0204
 QR 47 (83.9%) 77 (95.0%)
 RR1 (1.8%) 2 (2.5%)

with Fisher’s exact test, while using Armitage trend test.