Assessment of the Protective Role of Prenatal Zinc versus Insulin Supplementation on Fetal Cardiac Damage Induced by Maternal Diabetes in Rat Using Caspase-3 and KI67 Immunohistochemical Stains

Table 3

Mean ± SD of the maternal, placental, fetal, and fetal heart weights in the different groups.

Parameter	Group				ANOVA
	C	STZ-DM	STZ-DM + Zn	STZ-DM + In		value
Maternal weight gain (gm)	47.5 ± 3.08	33.83 ± 2.93	41.33 ± 3.98	38.17 ± 2.79	19.04	<0.00001
Placental weight (gm)	0.565 ± 0.081	0.624 ± 0.211	0.545 ± 0.092	0.540 ± 0.087	3.39	0.020
Fetal weight (gm)	3.29 ± 0.21	2.98 ± 0.33	3.16 ± 0.44	3.21 ± 0.42	4.89	0.003
Fetal heart weights (gm)	0.479 ± 0.062	0.424 ± 0.071	0.461 ± 0.095	0.475 ± 0.075	4.34	0.006

C: control group, STZ-DM: streptozotocin-induced diabetic group, STZ-DM + In: streptozotocin-induced diabetic treated with insulin group, and STZ-DM + Zn: streptozotocin-induced diabetic treated with Zn group.
, compared to the control group and compared to the STZ-DM group.