Research Article

Distinct Features of Gut Microbiota in High-Altitude Tibetan and Middle-Altitude Han Hypertensive Patients

Table 1

Baseline clinical characteristics of participants among subgroups of HPs.

Baseline clinical characteristicsLHH (n = 34)MHH (n = 49)HTH (n = 38) value

Age (years)55.9 ± 9.755.1 ± 8.752.8 ± 10.60.349
Sex (male/female)16/1828/2123/150.491
Smoking, n (%)15 (44.11)27 (55.10)16 (52.63)0.467
BMI (kg/m2)23.94 ± 0.6023.64 ± 1.0324.01 ± 0.940.137
SBP (mmHg)147.7 ± 14.1146.7 ± 10.2146.6 ± 15.80.934
DBP (mmHg)84.7 ± 15.482.6 ± 6.483.4 ± 11.20.693
TC (mmol/L)4.03 ± 0.824.24 ± 0.784.16 ± 0.860.540
TG (mmol/L)1.06 ± 0.111.07 ± 0.121.06 ± 0.120.797
HDL-C (mmol/L)1.14 ± 0.331.03 ± 0.241.04 ± 0.270.208
LDL-C (mmol/L)2.38 ± 0.632.53 ± 0.852.73 ± 0.680.135

Values are expressed as mean ± SD or n (%). values are calculated by one-way ANOVA or chi-squared test, and was considered statistically significant. Abbreviations: LHH, the Han HPs from low-altitude (Wuhan: 13 m); MHH, the Han HPs living at middle-altitude (Xining: 2260 m); HTH, the Tibetan HPs residing at high-altitude (Qinghai-Tibet Plateau: 3600–4500 m); BMI, Body Mass Index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.