Rejuvenated Circulating Endothelial Progenitor Cells and Nitric Oxide in Premenopausal Women with Hyperhomocysteinemia
Table 1
Clinical and biochemical characteristics.
Characteristics
Premenopausal women
Premenopausal women
Control (n = 20)
HHcy (n = 20)
Control (n = 20)
HHcy (n = 20)
Age (years)
46.1 ± 4.3
44.3 ± 4.8
55.3 ± 4.9#
56.7 ± 4.4#
Height (cm)
161.2 ± 5.5
160.3 ± 5.1
167.9 ± 4.6#
166.6 ± 5.5#
Weight (kg)
62.1 ± 5.4
60.0 ± 5.3
64.7 ± 5.5
65.3 ± 4.5#
BMI (kg/cm2)
23.9 ± 2.1
23.4 ± 2.1
22.9 ± 1.7
23.6 ± 2.0
Systolic blood pressure (mmHg)
117.9 ± 10.4
119.9 ± 8.1
121.7 ± 10.8
122.3 ± 11.2
Diastolic blood pressure (mmHg)
75.9 ± 10.0
72.9 ± 11.1
76.6 ± 8.4
74.1 ± 8.3
AST (mmol/L)
26.0 ± 5.6
26.1 ± 5.6
23.5 ± 5.6
24.3 ± 6.2
ALT (mmol/L)
23.4 ± 4.8
23.0 ± 6.9
20.5 ± 5.4
22.6 ± 5.5
BUN (mmol/L)
5.4 ± 0.9
5.5 ± 1.1
5.1 ± 1.1
5.5 ± 1.0
Cr (mmol/L)
68.9 ± 12.4
71.3 ± 14.7
67.1 ± 16.5
72.4 ± 16.5
LDL (mmol/L)
2.74 ± 0.24
2.86 ± 0.25
2.68 ± 0.41
2.79 ± 0.35
TC (mmol/L)
4.65 ± 0.35
4.80 ± 0.28
4.57 ± 0.51
4.71 ± 0.37
HDL (mmol/L)
1.41 ± 0.25
1.37 ± 0.20
1.44 ± 0.22
1.40 ± 0.15
TG (mmol/L)
1.38 ± 0.18
1.43 ± 0.17
1.36 ± 0.19
1.41 ± 0.14
FPG (mmol/L)
4.58 ± 0.65
4.77 ± 0.64
4.35 ± 0.52
4.63 ± 0.69
Homocysteine (μmol/L)
10.4 ± 1.6
20.7 ± 3 4☆
9.4 ± 1.8
21.8 ± 4.5☆
Estradiol (pmol/L)
209.2 ± 20.7
202.4 ± 29.8
99.6 ± 16.9#
107.5 ± 16.7#
FMD (%)
9.46 ± 1.33
8.39 ± 1.22☆
8.25 ± 1.07#
5.09 ± 0.92#☆
Abbreviation: BMI: body mass index; AST: aspartate amino transferals; ALT: alanine transaminase; BUN: blood urea nitrogen; Cr: serum creatinine; LDL: low density lipoprotein; TC: total cholesterol; HDL: high density lipoprotein; TG: triglyceride; FPG: fasting plasma glucose; FMD: flow-mediated brachial artery dilatation. Notes: Data are given as mean ± SD. ☆vs. normal weight; # vs. premenopausal women.
